Article
Genetic variants associated with myocardial infarction risk factors in over 8000 individuals from five ethnic groups: The INTERHEART Genetics Study.
Circulation. Cardiovascular genetics - 1 Feb 2009
Anand Sonia S, Xie Changchun, Paré Guillaume, Montpetit Alexandre, Rangarajan Sumathy, McQueen Matthew J, Cordell Heather J, Keavney Bernard, Yusuf Salim, Hudson Thomas J, Engert James C
Abstract excerpt
BACKGROUND: Myocardial infarction (MI) is a leading cause of death globally, but specific genetic variants that influence MI and MI risk factors have not been assessed on a global basis. METHODS AND RESULTS: We included 8795 individuals of European, South Asian, Arab, Iranian, and Nepalese origin from the INTERHEART case-control study that genotyped 1536 single-nucleotide polymorphisms (SNPs) from 103 genes. One...
Topics
- Alleles
- Apolipoprotein A-I
- Apolipoprotein E2
- Apolipoproteins B
- Arabs
- Asian People
- Case-Control Studies
- Cholesterol Ester Transfer Proteins
- Female
- Genotype