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Article

Prophylactic total gastrectomy in the management of hereditary tumor syndromes.

International journal of colorectal disease - 1 Dec 2016

Pantelis Dimitrios, Hüneburg Robert, Adam Ronja, Holzapfel Stefanie, Gevensleben Heidrun, Nattermann Jacob, Strassburg Christian P, Aretz Stefan, Kalff Jörg C

Abstract excerpt

PURPOSE: Germline mutations in several genes confer a relevant lifetime risk of gastric cancer. In this context, an increasing involvement of a surgeon can be seen, mainly with the question of performing a prophylactic operation. METHODS: Patients with hereditary tumor syndromes predisposing for gastric cancer who received care leading to prophylactic total gastrectomy in our Center for Hereditary Tumor Syndromes...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 27682646
DOI: 10.1007/s00384-016-2656-9

Genes

CDH1
SMAD4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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