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Article

Preemptive total gastrectomy for hereditary gastric cancer.

Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract - 1 Mar 2007

Medina-Franco Heriberto, Barreto-Zuñiga Rafael, García-Alvarez Miriam N

Abstract excerpt

Hereditary gastric cancer is a recently described clinical syndrome, associated with truncating mutation of the E-cadherin gene, named CDH1. It is characterized by autosomal dominant transmission, presentation at an early age, and with diffuse type of gastric adenocarcinoma. Clinical management o...

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Source

Identifiers

PMID: 17458604
DOI: 10.1007/s11605-007-0122-2

Genes

CDH1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-17458604-2026-09-04.1. Manifest publication-graph-cohort-2026-09-04.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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Unique challenges of risk-reducing surgery for hereditary diffuse gastric cancer syndrome: a narrative review.Semantic proximity Read ↗

Hereditary diffuse gastric cancer.Semantic proximity Read ↗

Hereditary diffuse gastric cancer: lifesaving total gastrectomy for CDH1 mutation carriers.Semantic proximity Read ↗

Short and long-term outcomes of prophylactic total gastrectomy in 54 consecutive individuals with germline pathogenic mutations in the CDH1 gene.Semantic proximity Read ↗

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