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Article

Unique challenges of risk-reducing surgery for hereditary diffuse gastric cancer syndrome: a narrative review.

European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) - 1 Jul 2023

Gallanis Amber F, Davis Jeremy L

Abstract excerpt

The common use of genetic testing has reinvigorated discussions surrounding enhanced cancer surveillance, chemoprevention, and preventive surgery strategies due to increasing recognition of pathogenic germline genetic variants. Prophylactic surgery for hereditary cancer syndromes can significantly reduce the risk of developing cancer. Hereditary diffuse gastric cancer (HDGC), characterized by high penetrance and...

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Identifiers

PMID: 36977191
DOI: 10.1097/CEJ.0000000000000798
PMCID: PMC10249595

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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