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Article

Estrogen receptor beta polymorphisms and cognitive performance in women: associations and modifications by genetic and environmental influences.

Journal of neural transmission (Vienna, Austria : 1996) - 1 Dec 2016

Fehsel Karin, Schikowski Tamara, Jänner Michaela, Hüls Anke, Voussoughi Mohammed, Schulte Thomas, Vierkötter Andrea, Teichert Tom, Herder Christian, Sugiri Dorothea, Krämer Ursula, Luckhaus Christian

Abstract excerpt

Genetic and environmental risk factors contribute to the pathogenesis of Alzheimer's dementia. Besides known genetic risk factors like the apolipoprotein (APO) Eε4 allele, single nuclear polymorphisms (SNPs) of the estrogen receptors (ESRs) are candidate genetic risk factors, while air pollution represents an environmental risk factor for dementia. Effects of these risk factors and their interaction were...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 27629499
DOI: 10.1007/s00702-016-1620-8

Genes

ESR2
ESR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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