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Article

Estrogen receptor α gene polymorphisms and risk of Alzheimer's disease: evidence from a meta-analysis.

Clinical interventions in aging - 1 Jan 2014

Cheng Daye, Liang Bin, Hao Yiwen, Zhou Wenling

Abstract excerpt

OBJECTIVE: Human estrogen receptor α (ESR1), a member of the nuclear receptor superfamily of ligand-activated transcription factors, is one of the key mediators of hormonal response in estrogen-sensitive tissues. Accumulating evidence has demonstrated that two of the most widely studied single-nucleotide polymorphisms in ESR1 - PvuII (T/C, rs223493) and Xbal (A/G, rs9340799) - are possibly associated with...

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Source

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Identifiers

PMID: 25061285
DOI: 10.2147/CIA.S65921
PMCID: PMC4085310

Genes

ESR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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