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Article

Prospective analysis of the association between estrogen receptor gene variants and the risk of cognitive decline in elderly women.

European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology - 1 Dec 2013

Ryan Joanne, Carrière Isabelle, Amieva Helene, Rouaud Olivier, Berr Claudine, Ritchie Karen, Scarabin Pierre-Yves, Ancelin Marie-Laure

Abstract excerpt

A plethora of data suggests a role for estrogen in cognitive function and genetic variants in the estrogen receptors ESR1 and ESR2 have been implicated in a range of hormone-sensitive diseases. It remains unknown however, whether ESR polymorphisms are associated with the risk of decline in specific domains of cognitive function. Data came from 3799 non-demented, community-dwelling elderly women recruited in...

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Source

Identifiers

PMID: 23932494
DOI: 10.1016/j.euroneuro.2013.06.003

Genes

ESR2
ESR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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