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Article

Study of estrogen receptor-α and receptor-β gene polymorphisms on Alzheimer's disease.

Journal of Alzheimer's disease : JAD - 1 Jan 2011

Goumidi Louisa, Dahlman-Wright Karin, Tapia-Paez Isabel, Matsson Hans, Pasquier Florence, Amouyel Philippe, Kere Juha, Lambert Jean-Charles, Meirhaeghe Aline

Abstract excerpt

Estrogen treatment can modulate the risk for developing dementia in women. Therefore, single nucleotide polymorphisms (SNPs) in the estrogen receptor genes may constitute genetic susceptibility factors to Alzheimer's disease (AD). Thus, we investigated the impact of the genetic variability of the estrogen receptor α 1 (ESR1) and estrogen receptor α 2 (ESR2) genes on late onset AD risk. We analyzed 39 SNPs in ESR1...

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Alzheimer Disease
Apolipoproteins E
Estrogen Receptor alpha
Estrogen Receptor beta
Genes, Dominant

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genes, Recessive

Linkage Disequilibrium

Risk Assessment

Source

Identifiers

PMID: 21673408
DOI: 10.3233/JAD-2011-110362

Genes

ESR1
ESR2
APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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