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Article

Estrogen receptor polymorphisms and incident dementia: the prospective 3C study.

Alzheimer's & dementia : the journal of the Alzheimer's Association - 1 Jan 2014

Ryan Joanne, Carrière Isabelle, Carcaillon Laure, Dartigues Jean-Francois, Auriacombe Sophie, Rouaud Olivier, Berr Claudine, Ritchie Karen, Scarabin Pierre-Yves, Ancelin Marie-Laure

Abstract excerpt

BACKGROUND: Genetic variation in the estrogen receptor (ESR) may be associated with the incidence of Alzheimer's disease (AD), but this association could be modified by genetic and environmental factors. METHODS: The association between five ESR α (ESR1) and β (ESR2) polymorphisms with 7-year dementia incidence was examined among 6959 older men and women from the Three City Study using multivariate-adjusted Cox...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23491264
DOI: 10.1016/j.jalz.2012.12.008

Genes

APOE
ESR2
ESR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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