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Article

Estrogen receptor alpha and risk for cognitive impairment in postmenopausal women.

Psychiatric genetics - 1 Apr 2006

Olsen Line, Rasmussen Henrik B, Hansen Thomas, Bagger Yu Z, Tankó László B, Qin Gerong, Christiansen Claus, Werge Thomas

Abstract excerpt

The estrogen receptor alpha (ESR1) gene has been implicated in the process of cognitive impairment in elderly women. In a paired case-control study, we tested whether two ESR1 gene polymorphisms (the XbaI and PvuII sites) are risk factors for cognitive impairment as measured by the six-item Orientation-Memory-Concentration test in postmenopausal Danish women. Hormone replacement therapy, age and executive...

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Source

Identifiers

PMID: 16538187
DOI: 10.1097/01.ypg.0000194445.27555.71

Genes

ESR1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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