Article
Estrogen receptor 1 polymorphisms and risk of cognitive impairment in older women.
Biological psychiatry - 15 Apr 2002
Yaffe Kristine, Lui Li Yung, Grady Deborah, Stone Katie, Morin Philip
Abstract excerpt
BACKGROUND: Several genes associated with sporadic Alzheimer's disease have been identified; however, approximately 50% of genetic factors remain unidentified. We investigated whether estrogen receptor 1 (ESR1) polymorphisms are associated with risk of developing cognitive impairment in older women. METHODS: A total of 2625 women > or = 65 years of age completed a modified Mini-Mental Status Exam (mMMSE) at...
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