Article
Persistent DNMT3A mutation burden in DNMT3A mutated adult cytogenetically normal acute myeloid leukemia patients in long-term remission.
Leukemia research - 1 Oct 2016
Sun Yanjun, Shen Hongjie, Xu Ting, Yang Zhen, Qiu Huiying, Sun Aining, Chen Suning, Wu Depei, Xu Yang
Abstract excerpt
DNMT3A mutations are frequent in cytogenetically normal acute myeloid leukemia (CN-AML) patients and can be present many years before the disease develops. However, the clinical significance of DNMT3A mutation burden in CN-AML remains unclear. In this study, 81 DNMT3A mutated adult CN-AML patients in their first complete remission (CR) were enrolled at our center from March 2005 to May 2015. All patients were...
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