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Article

Clinical features and prognostic significance of DNMT3A, FLT3, and NPM1 mutations in de novo acute myeloid leukemia patients.

International journal of laboratory hematology - 1 Dec 2023

Chen Meiyu, Zeng Zhao, Li Xuewei, Qin Wei, Cai Xiaohui, Chen Suning, Lu Xuzhang

Abstract excerpt

OBJECTIVE: Different co-mutation patterns are associated with varied clinical manifestations and prognosis. The purpose of this research was to explore the clinical characteristics and prognosis of individuals with AML who had DNMT3A, FLT3, and NPM1 mutations. MATERIALS AND METHODS: A total of 259 newly diagnosed AML patients were investigated in this study, including 148 AMLFLT3mutDNMT3Awt , 48...

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PMID: 37519024
DOI: 10.1111/ijlh.14133

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