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Article

A novel method for multiple phenotype association studies based on genotype and phenotype network.

PLoS genetics - 1 May 2024

Cao Xuewei, Zhang Shuanglin, Sha Qiuying

Abstract excerpt

Joint analysis of multiple correlated phenotypes for genome-wide association studies (GWAS) can identify and interpret pleiotropic loci which are essential to understand pleiotropy in diseases and complex traits. Meanwhile, constructing a network based on associations between phenotypes and genotypes provides a new insight to analyze multiple phenotypes, which can explore whether phenotypes and genotypes might be...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38728360
DOI: 10.1371/journal.pgen.1011245
PMCID: PMC11111089

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