Article

Integration of Molecular Interactome and Targeted Interaction Analysis to Identify a COPD Disease Network Module

2018-09-04

Abstract excerpt

The polygenic nature of complex diseases offers potential opportunities to utilize network-based approaches that leverage the comprehensive set of protein-protein interactions (the human interactome) to identify new genes of interest and relevant biological pathways. However, the incompleteness of the current human interactome prevents it from reaching its full potential to extract network-based knowledge from gen...

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Literature Corpus work: 0b195174-c2c0-582c-a5ac-d933fa11f0e3
DOI: 10.1101/408229

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