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Article

GWIS: Genome-Wide Inferred Statistics for Functions of Multiple Phenotypes.

American journal of human genetics - 6 Oct 2016

Nieuwboer Harold A, Pool René, Dolan Conor V, Boomsma Dorret I, Nivard Michel G

Abstract excerpt

Here we present a method of genome-wide inferred study (GWIS) that provides an approximation of genome-wide association study (GWAS) summary statistics for a variable that is a function of phenotypes for which GWAS summary statistics, phenotypic means, and covariances are available. A GWIS can be performed regardless of sample overlap between the GWAS of the phenotypes on which the function depends. Because a...

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Identifiers

PMID: 27616482
DOI: 10.1016/j.ajhg.2016.07.020
PMCID: PMC5065656

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

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