Article

Bayesian large-scale multiple regression with summary statistics from genome-wide association studies

2016-03-04

Abstract excerpt

Bayesian methods for large-scale multiple regression provide attractive approaches to the analysis of genome-wide association studies (GWAS). For example, they can estimate heritability of complex traits, allowing for both polygenic and sparse models; and by incorporating external genomic data into the priors they can increase power and yield new biological insights. However, these methods require access to indivi...

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Literature Corpus work: 4a6daba0-989d-5419-98a9-1fea7b8c7afd
DOI: 10.1101/042457

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