Article

Components of genetic associations across 2,138 phenotypes in the UK Biobank highlight novel adipocyte biology

2018-10-14

Abstract excerpt

Population-based biobanks with genomic and dense phenotype data provide opportunities for generating effective therapeutic hypotheses and understanding the genomic role in disease predisposition. To characterize latent components of genetic associations, we applied truncated singular value decomposition (DeGAs) to matrices of summary statistics derived from genome-wide association analyses across 2,138 phenotypes...

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Literature Corpus work: b11783d6-eb19-5cb5-ab5a-33080575335a
DOI: 10.1101/442715

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