Article
Estimation of the HIV-1 backward mutation rate from transmitted drug-resistant strains.
Theoretical population biology - 1 Dec 2016
Kitayimbwa J M, Mugisha J Y T, Saenz R A
Abstract excerpt
One of the serious threats facing the administration of antiretroviral therapy to human immunodeficiency virus (HIV-1) infected patients is the reported increasing prevalence of transmitted drug resistance. However, given that HIV-1 drug-resistant strains are often less fit than the wild-type strains, it is expected that drug-resistant strains that are present during the primary phase of the HIV-1 infection are...
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