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Article

Mathematical approaches in the study of viral kinetics and drug resistance in HIV-1 infection.

Current drug targets. Infectious disorders - 1 Dec 2003

Müller V, Bonhoeffer S

Abstract excerpt

We review some crucial aspects of drug therapy and viral resistance that have been investigated within the framework developed for the modelling of virus kinetics. First, we give a general overview on the use of mathematical models in the field of HIV research. We seek to identify the factors that determine the steady state virus load and show that stable reductions during antiviral therapy are difficult to...

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Identifiers

PMID: 14754433
DOI: 10.2174/1568005033481042

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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