Article
Comparison of different treatment regimens for the emergence of new resistance under therapy.
Journal of acquired immune deficiency syndromes (1999) - 1 Aug 2001
Roberts D E, Ribeiro R M
Abstract excerpt
OBJECTIVE: To compare the effects of different therapy regimens on the probability of emergence of new resistant mutants during therapy. METHODS: We developed a stochastic model of infection and treatment to calculate the probability of de novo resistance during therapy. We simulated diverse trea...
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