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Article

Modeling Drug Resistance Emergence and Transmission in HIV-1 in the UK.

Viruses - 25 May 2023

Zhukova Anna, Dunn David, Gascuel Olivier

Abstract excerpt

A deeper understanding of HIV-1 transmission and drug resistance mechanisms can lead to improvements in current treatment policies. However, the rates at which HIV-1 drug resistance mutations (DRMs) are acquired and which transmitted DRMs persist are multi-factorial and vary considerably between different mutations. We develop a method for the estimation of drug resistance acquisition and transmission patterns....

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Identifiers

PMID: 37376544
DOI: 10.3390/v15061244
PMCID: PMC10304371

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