Article

Defining cell type-specific immune responses in a mouse model of allergic contact dermatitis by single-cell transcriptomics

2024-01-20

Abstract excerpt

Allergic contact dermatitis (ACD), a prevalent inflammatory skin disease, is elicited upon repeated skin contact with protein-reactive chemicals through a complex and poorly characterized cellular network between immune cells and skin resident cells. Here, single-cell transcriptomic analysis of the murine hapten-elicited model of ACD reveals that upon elicitation of ACD, infiltrated CD4 + or CD8 + lymphocytes we...

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Literature Corpus work: 2b516e3d-9d48-51f9-99b6-7e9d8bb878c4
DOI: 10.1101/2024.01.16.575925

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