Article

Tertiary lymphoid structures support the development of allergen-specific progenitor CD4+ T cells

2025-10-05

Abstract excerpt

Tissue-resident memory CD4+ T cells (T RM ) are key sentinels of the adaptive immune response that provide a rapid, robust inflammatory response upon reactivation in non-lymphoid tissues. While CD4+ T RM are highly protective during reinfections or tumor growth, they are also critical mediators of autoimmunity and allergic disease. Using transcriptional analysis and flow cytometry we profiled the heterogeneity o...

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Literature Corpus work: 183a2df3-3c14-5f54-984e-c6a133313fa3
DOI: 10.1101/2025.10.03.680350

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