Article

Comprehensive transcriptomic profiling uncovers an inflammatory maturation program conserved in human and mouse dendritic cells

2026-08-04

Abstract excerpt

<h4>ABSTRACT</h4> Conventional dendritic cells (cDCs) integrate signals to balance tolerance and immunity, but how steady-state cDC programs are changed during inflammatory maturation remains incompletely resolved. Here, using Seqtometry-based analysis of mouse and human cDCs, we identify distinct steady-state cDC1 gene programs enriched for either tolerance-associated or immune response-associated (pre-immunogen...

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Literature Corpus work: a6c93e3e-2f8b-5ebf-888c-728f9d26d63f
DOI: 10.64898/2026.07.30.741848

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