Article

Cutaneous allergen sensitization is critical for allergic humoral responses controlled by IL-13 receptor-expressing conventional dendritic cells

2023-03-31

Abstract excerpt

<title>Abstract</title> <p>Skin barrier dysfunction in the setting of atopic dermatitis (AD) leads to cutaneous allergen sensitization (CAS).1 The atopic march hypothesis proposes that CAS leads to the subsequent development of other allergic disorders such as asthma and food allergy.2-5 The latter is associated with IgE-mediated anaphylaxis6. However, the precise mechanisms by which CAS promotes IgE-mediated all...

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Literature Corpus work: c0bcb51d-5f00-52be-804a-ee209aad7f61
DOI: 10.21203/rs.3.rs-2717830/v1

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