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Article

CoNCoS: copy number estimation in cancer with controlled support.

Journal of bioinformatics and computational biology - 1 Oct 2015

Abdallah Ali T, Fischer Matthias, Nürnberg Peter, Nothnagel Michael, Frommolt Peter

Abstract excerpt

Somatic copy number (CN) alterations are major drivers of tumorigenesis and growth. Although next-generation sequencing (NGS) technologies enable a deep genomic analysis of cancers, the analysis of the data remains subject to biases and multiple sources of error, including varying local read coverage. The currently existing algorithms for NGS-based detection of CN abberations do not incorporate information on the...

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PMID: 26449175
DOI: 10.1142/S0219720015500274

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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