Article
Impacts of the mTOR gene polymorphisms rs2536 and rs2295080 on breast cancer risk in the Chinese population.
Oncotarget - 6 Sept 2016
Zhao Yang, Diao Yan, Wang XiJing, Lin Shuai, Wang Meng, Kang HuaFeng, Yang PengTao, Dai Cong, Liu XingHan, Liu Kang, Li ShanLi, Zhu YuYao, Dai ZhiJun
Abstract excerpt
Mammalian target of rapamycin (mTOR) gene polymorphisms exert the major effects on the regulation of transcriptional activity and miRNA binding or splicing, which may be associated with cancer risk by affecting mTOR gene expression. However, inconsistent results have been previously reported. The present study evaluated the correlation between mTOR rs2536/rs2295080 polymorphisms and breast cancer risk. This...
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