Functional promoter rs2295080 T>G variant in MTOR gene is associated with risk of colorectal cancer in a Chinese population.

doi:10.1016/j.biopha.2014.12.045

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Article

Functional promoter rs2295080 T>G variant in MTOR gene is associated with risk of colorectal cancer in a Chinese population.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie - 1 Mar 2015

Xu Ming, Gao Yan, Yu Tingting, Wang Jirong, Cheng Liang, Cheng Lifang, Cheng Dawei, Zhu Baoli

Abstract excerpt

BACKGROUND: The mammalian target of rapamycin (mTOR) plays an important role in the development and progression of colorectal cancer (CRC). Recently, a functional polymorphism (rs2295080 T>G) in the promoter of MTOR has been shown to influence its expression and confer susceptibility to cancer. Therefore, in the present study, we sought to investigate the influence of this polymorphism on the risk of CRC....

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Identifiers

PMID: 25776475
DOI: 10.1016/j.biopha.2014.12.045

Genes

MTOR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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