Association of neuropeptide Y promoter polymorphism (rs16147) with perceived stress and cardiac vagal outflow in humans.

doi:10.1038/srep31683

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Article

Association of neuropeptide Y promoter polymorphism (rs16147) with perceived stress and cardiac vagal outflow in humans.

Scientific reports - 16 Aug 2016

Chang Hsin-An, Fang Wen-Hui, Chang Tieh-Ching, Huang San-Yuan, Chang Chuan-Chia

Abstract excerpt

Neuropeptide Y (NPY) is involved in resilience to stress, and higher vagal (parasympathetic) activity has been associated with greater stress resilience. Thus, we examined whether rs16147, a functional promoter polymorphism (C>T) of the NPY gene, could influence vagal tone during chronic high stress levels. NPY genotyping, chronic psychological stress level measurement (using the Perceived Stress Scale [PSS]),...

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PMID: 27527739
DOI: 10.1038/srep31683
PMCID: PMC4985655

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