Human NPY promoter variation rs16147:T>C as a moderator of prefrontal NPY gene expression and negative affect.

doi:10.1002/humu.21299

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Article

Human NPY promoter variation rs16147:T>C as a moderator of prefrontal NPY gene expression and negative affect.

Human mutation - 1 Aug 2010

Sommer Wolfgang H, Lidström Jessica, Sun Hui, Passer Derek, Eskay Robert, Parker Stephen C J, Witt Stephanie H, Zimmermann Ulrich S, Nieratschker Vanessa, Rietschel Marcella, Margulies Elliott H, Palkovits Miklós, Laucht Manfred, Heilig Markus

Abstract excerpt

Studies in humans and animals suggest a role for NPY in the mediation of behavioral stress responses. Here, we examined whether the NPY promoter variant rs16147:T>C is functional for expression of NPY in a brain region relevant for behavioral control, anxiety and depression, the anterior cingulat...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 20648632
DOI: 10.1002/humu.21299
PMCID: PMC2908962

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20648632-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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