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Article

Sex-specific association between nerve growth factor polymorphism and cardiac vagal modulation.

Psychosomatic medicine - 1 Oct 2014

Chang Chuan-Chia, Fang Wen-Hui, Chang Hsin-An, Chen Tien-Yu, Huang San-Yuan

Abstract excerpt

OBJECTIVE: Substantial research has shown that anxiety disorders are associated with decreased cardiac vagal tone, which is a known risk factor for cardiac vulnerability. A functional nerve growth factor (NGF) polymorphism (rs6330, c.104C > T, p.Ala35Val) has been associated with anxiety such that in males but not females, T-allele carriers exhibit higher levels of trait anxiety. Here we investigate whether the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25162994
DOI: 10.1097/PSY.0000000000000091

Genes

NGF

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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