Article
Association of estrogen receptor-alpha gene polymorphisms with cardiac autonomic nervous activity in healthy young Japanese males.
Clinica chimica acta; international journal of clinical chemistry - 2 Apr 2010
Matsunaga Tetsuro, Gu Ning, Yamazaki Hanae, Adachi Tetsuya, Yasuda Koichiro, Moritani Toshio, Tsuda Kinsuke, Nishiyama Tohru, Nonaka Masahiko
Abstract excerpt
BACKGROUND: Estrogens exert beneficial effects on the cardiovascular system that are mediated by estrogen receptors. We examined the association between the estrogen receptor alpha gene (ESR1) PvuII and XbaI polymorphisms and cardiac autonomic nervous function in Japanese males. METHODS: We examined 252 young healthy males for association of ESR1 PvuII and XbaI polymorphisms and short-term heart rate variability...
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