Article
Neuropeptide Y, stressful life events and personality trait conscientiousness: Preliminary associations from a Swedish longitudinal study.
Psychiatry research - 1 May 2018
Melas Philippe A, Guban Peter, Rahman Md Shafiqur, Lavebratt Catharina, Forsell Yvonne
Abstract excerpt
The heritability of the Five-Factor Model (FFM) of human personality is high, but few genes have been identified to underlie FFM traits. Neuropeptide Y (NPY) is a pleiotropic gene implicated in stress resilience that contains two well-studied functional SNPs: (1) rs16147, which lies in the NPY promoter and affects expression levels, and (2) rs16139, which lies in the coding sequence of NPY's precursor peptide,...
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