Article
Clinical Utility and Economic Impact of CYP2D6 Genotyping.
Clinics in laboratory medicine - 1 Sept 2016
Reynolds Kristen K, McNally Beth A, Linder Mark W
Abstract excerpt
Pharmacogenetics examines an individual's genetic makeup to help predict the safety and efficacy of medications. Practical application optimizes treatment selection to decrease the failure rate of medications and improve clinical outcomes. Lack of efficacy is costly due to adverse drug reactions and increased hospital stays. Cytochrome P450 2D6 (CYP2D6) metabolizes roughly 25% of all drugs. Detecting variants...
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