Article

CYP2D6 pharmacogenomics

2017-04-12

Abstract excerpt

Cytochromes are proteins that catalyze electron transfer reactions of many metabolic pathways. They are involved in drug metabolism and thus determines the therapeutic safety and efficacy of drugs in patients. Cytochrome P450 in mitochondria accounts for 90% of the oxidative metabolism of clinically used drugs during phase 1 reaction. CYP2D6 is a major gene member of this superfamily as it carries out metabolism o...

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Literature Corpus work: 044d4ec9-6646-5d2f-a01d-67ea02fc7052
DOI: 10.1016/j.ejmhg.2017.03.001

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