Article
Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2D6, CYP2C19, CYP2B6, SLC6A4, and HTR2A Genotypes and Serotonin Reuptake Inhibitor Antidepressants.
Clinical pharmacology and therapeutics - 1 Jul 2023
Bousman Chad A, Stevenson James M, Ramsey Laura B, Sangkuhl Katrin, Hicks J Kevin, Strawn Jeffrey R, Singh Ajeet B, Ruaño Gualberto, Mueller Daniel J, Tsermpini Evangelia Eirini, Brown Jacob T, Bell Gillian C, Leeder J Steven, Gaedigk Andrea, Scott Stuart A, Klein Teri E, Caudle Kelly E, Bishop Jeffrey R
Abstract excerpt
Serotonin reuptake inhibitor antidepressants, including selective serotonin reuptake inhibitors (SSRIs; i.e., citalopram, escitalopram, fluoxetine, fluvoxamine, paroxetine, and sertraline), serotonin and norepinephrine reuptake inhibitors (i.e., desvenlafaxine, duloxetine, levomilnacipran, milnacipran, and venlafaxine), and serotonin modulators with SSRI-like properties (i.e., vilazodone and vortioxetine) are...
Topics
- Humans
- Selective Serotonin Reuptake Inhibitors
- Cytochrome P-450 CYP2D6
- Cytochrome P-450 CYP2B6
- Pharmacogenetics
- Depressive Disorder, Major
- Cytochrome P-450 CYP2C19
- Serotonin Plasma Membrane Transport Proteins