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Article

Multi-omic insights into Parkinson's Disease: From genetic associations to functional mechanisms.

Neurobiology of disease - 1 Feb 2022

Schilder Brian M, Navarro Elisa, Raj Towfique

Abstract excerpt

Genome-Wide Association Studies (GWAS) have elucidated the genetic components of Parkinson's Disease (PD). However, because the vast majority of GWAS association signals fall within non-coding regions, translating these results into an interpretable, mechanistic understanding of the disease etiology remains a major challenge in the field. In this review, we provide an overview of the approaches to prioritize...

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Identifiers

PMID: 34871738
DOI: 10.1016/j.nbd.2021.105580
PMCID: PMC10101343

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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