Article
Identification of novel risk loci, causal insights, and heritable risk for Parkinson's disease: a meta-analysis of genome-wide association studies.
The Lancet. Neurology - 1 Dec 2019
Nalls Mike A, Blauwendraat Cornelis, Vallerga Costanza L, Heilbron Karl, Bandres-Ciga Sara, Chang Diana, Tan Manuela, Kia Demis A, Noyce Alastair J, Xue Angli, Bras Jose, Young Emily, von Coelln Rainer, Simón-Sánchez Javier, Schulte Claudia, Sharma Manu, Krohn Lynne, Pihlstrøm Lasse, Siitonen Ari, Iwaki Hirotaka, Leonard Hampton, Faghri Faraz, Gibbs J Raphael, Hernandez Dena G, Scholz Sonja W, Botia Juan A, Martinez Maria, Corvol Jean-Christophe, Lesage Suzanne, Jankovic Joseph, Shulman Lisa M, Sutherland Margaret, Tienari Pentti, Majamaa Kari, Toft Mathias, Andreassen Ole A, Bangale Tushar, Brice Alexis, Yang Jian, Gan-Or Ziv, Gasser Thomas, Heutink Peter, Shulman Joshua M, Wood Nicholas W, Hinds David A, Hardy John A, Morris Huw R, Gratten Jacob, Visscher Peter M, Graham Robert R, Singleton Andrew B
Abstract excerpt
BACKGROUND: Genome-wide association studies (GWAS) in Parkinson's disease have increased the scope of biological knowledge about the disease over the past decade. We aimed to use the largest aggregate of GWAS data to identify novel risk loci and gain further insight into the causes of Parkinson's disease. METHODS: We did a meta-analysis of 17 datasets from Parkinson's disease GWAS available from European ancestry...
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