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Article

A meta-analysis of genome-wide association studies identifies 17 new Parkinson's disease risk loci.

Nature genetics - 1 Oct 2017

Chang Diana, Nalls Mike A, Hallgrímsdóttir Ingileif B, Hunkapiller Julie, van der Brug Marcel, Cai Fang, Kerchner Geoffrey A, Ayalon Gai, Bingol Baris, Sheng Morgan, Hinds David, Behrens Timothy W, Singleton Andrew B, Bhangale Tushar R, Graham Robert R

Abstract excerpt

Common variant genome-wide association studies (GWASs) have, to date, identified >24 risk loci for Parkinson's disease (PD). To discover additional loci, we carried out a GWAS comparing 6,476 PD cases with 302,042 controls, followed by a meta-analysis with a recent study of over 13,000 PD cases and 95,000 controls at 9,830 overlapping variants. We then tested 35 loci (P < 1 × 10-6) in a replication cohort of...

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Identifiers

PMID: 28892059
DOI: 10.1038/ng.3955
PMCID: PMC5812477

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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