Article
Integrative Functional Genomics Implicates EPB41 Dysregulation in Hepatocellular Carcinoma Risk.
American journal of human genetics - 4 Aug 2016
Yang Xinyu, Yu Dianke, Ren Yanli, Wei Jinyu, Pan Wenting, Zhou Changchun, Zhou Liqing, Liu Yu, Yang Ming
Abstract excerpt
Genome-wide association studies (GWASs) have provided many insights into cancer genetics. However, the molecular mechanisms of many susceptibility SNPs defined by GWASs in cancer heritability and in promoting cancer risk remain elusive. New research strategies, including functional evaluations, are warranted to systematically explore truly causal genetic variants. In this study, we developed an integrative...
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