Article

Multi-ancestry genome-wide association meta-analysis of hepatocellular carcinoma identifies eight novel risk genes including <i>MYC</i> , <i>MAP3K9</i> , <i>DHRS1</i> , and <i>MTTP</i>

2025-12-17

Abstract excerpt

<h4>Background & Aims</h4> Hepatocellular carcinoma (HCC) is the third top cause of cancer death globally, often arising on a background of cirrhosis. Here, we aimed to establish novel genetic drivers of HCC across ancestries at a population level through a large meta-analysis of all-cause HCC. <h4>Approach & Results</h4> We included 15 cohorts comprising 17,329 HCC cases and 2,424,298 controls in this meta-anal...

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Literature Corpus work: 09e2fa1c-56d8-5bc4-8b5d-d5d9d9be9a64
DOI: 10.64898/2025.12.16.25342341

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Multi-ancestry genome-wide association meta-analysis of hepatocellular carcinoma identifies eight novel risk genes including <i>MYC</i> , <i>MAP3K9</i> , <i>DHRS1</i> , and <i>MTTP</i>DOI 10.64898/2025.12.16.25342341Read

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