Article
Genome-wide association study of hepatocellular carcinoma in Southern Chinese patients with chronic hepatitis B virus infection.
PloS one - 1 Jan 2011
Chan Kelvin Yuen-Kwong, Wong Chun-Ming, Kwan Johnny Sheung-Him, Lee Joyce Man-Fong, Cheung Ka Wai, Yuen Man Fung, Lai Ching Lung, Poon Ronnie Tung-Ping, Sham Pak Chung, Ng Irene Oi-Lin
Abstract excerpt
One of the most relevant risk factors for hepatocellular carcinoma (HCC) development is chronic hepatitis B virus (HBV) infection, but only a fraction of chronic HBV carriers develop HCC, indicating that complex interactions among viral, environmental and genetic factors lead to HCC in HBV-infect...
Topics
- Asian People
- Base Sequence
- Carcinoma, Hepatocellular
- Cell Line, Tumor
- China
- Chromosomes, Human, Pair 8
- Computational Biology
- Data Mining
- Expressed Sequence Tags
- Female
- Gene Expression Regulation, Neoplastic
- Genetic Loci
- Genetic Predisposition to Disease