Article
Genome-wide association study of hepatocellular carcinoma in Southern Chinese patients with chronic hepatitis B virus infection.
PloS one - 1 Jan 2011
Chan Kelvin Yuen-Kwong, Wong Chun-Ming, Kwan Johnny Sheung-Him, Lee Joyce Man-Fong, Cheung Ka Wai, Yuen Man Fung, Lai Ching Lung, Poon Ronnie Tung-Ping, Sham Pak Chung, Ng Irene Oi-Lin
Abstract excerpt
One of the most relevant risk factors for hepatocellular carcinoma (HCC) development is chronic hepatitis B virus (HBV) infection, but only a fraction of chronic HBV carriers develop HCC, indicating that complex interactions among viral, environmental and genetic factors lead to HCC in HBV-infected patients. So far, host genetic factors have incompletely been characterized. Therefore, we performed a genome-wide...
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