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Article

Identification of 13 Novel Loci in a Genome-Wide Association Study on Taiwanese with Hepatocellular Carcinoma.

International journal of molecular sciences - 16 Nov 2023

Liu Ting-Yuan, Liao Chi-Chou, Chang Ya-Sian, Chen Yu-Chia, Chen Hong-Da, Lai I-Lu, Peng Cheng-Yuan, Chung Chin-Chun, Chou Yu-Pao, Tsai Fuu-Jen, Jeng Long-Bin, Chang Jan-Gowth

Abstract excerpt

Liver cancer is caused by complex interactions among genetic factors, viral infection, alcohol abuse, and metabolic diseases. We conducted a genome-wide association study and polygenic risk score (PRS) model in Taiwan, employing a nonspecific etiology approach, to identify genetic risk factors for hepatocellular carcinoma (HCC). Our analysis of 2836 HCC cases and 134,549 controls revealed 13 novel associated loci...

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Identifiers

PMID: 38003606
DOI: 10.3390/ijms242216417
PMCID: PMC10671380

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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