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Article

Evolution of oesophageal adenocarcinoma from metaplastic columnar epithelium without goblet cells in Barrett's oesophagus.

Gut - 1 Jun 2016

Lavery Danielle L, Martinez Pierre, Gay Laura J, Cereser Biancastella, Novelli Marco R, Rodriguez-Justo Manuel, Meijer Sybren L, Graham Trevor A, McDonald Stuart A C, Wright Nicholas A, Jansen Marnix

Abstract excerpt

OBJECTIVE: Barrett's oesophagus commonly presents as a patchwork of columnar metaplasia with and without goblet cells in the distal oesophagus. The presence of metaplastic columnar epithelium with goblet cells on oesophageal biopsy is a marker of cancer progression risk, but it is unclear whether clonal expansion and progression in Barrett's oesophagus is exclusive to columnar epithelium with goblet cells....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26701877
DOI: 10.1136/gutjnl-2015-310748
PMCID: PMC4893117

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