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Article

Barrett's oesophagus: an ideal model to study cancer genetics.

Human genetics - 1 Aug 2009

di Pietro Massimiliano, Fitzgerald Rebecca C

Abstract excerpt

Chronic gastro-oesophageal reflux disease can induce a metaplastic change of the distal oesophagus called Barrett's oesophagus whereby the normal squamous epithelium is substituted by a columnar epithelium. Patients with Barrett's oesophagus are at increased risk of oesophageal adenocarcinoma which occurs through dysplastic stages with increasing degree of cellular and architectural disorganization. Barrett's...

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Source

Identifiers

PMID: 19365640
DOI: 10.1007/s00439-009-0665-2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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