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Article

Complex structural rearrangements are present in high-grade dysplastic Barrett’s oesophagus samples

4 Feb 2019

Abstract excerpt

BACKGROUND: Oesophageal adenocarcinoma (EAC) incidence is increasing and has a poor survival rate. Barrett's oesophagus (BE) is a precursor condition that is associated with EAC and often occurs in conjunction with chronic gastro-oesophageal reflux, however many individuals diagnosed with BE never progress to cancer. An understanding of the genomic features of BE and EAC may help with the early identification of...

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PMID: 30717762
DOI: 10.1186/s12920-019-0476-9

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