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Article

Genetic Insights in Barrett's Esophagus and Esophageal Adenocarcinoma.

Gastroenterology - 1 Oct 2015

Reid Brian J, Paulson Thomas G, Li Xiaohong

Abstract excerpt

Beginning in the 1980s, an alarming rise in the incidence of esophageal adenocarcinoma (EA) led to screening of patients with reflux to detect Barrett's esophagus (BE) and surveillance of BE to detect early EA. This strategy, based on linear progression disease models, resulted in selective detection of BE that does not progress to EA over a lifetime (overdiagnosis) and missed BE that rapidly progresses to EA...

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Identifiers

PMID: 26208895
DOI: 10.1053/j.gastro.2015.07.010
PMCID: PMC4589483

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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