Article
Genome-wide association study confirms lung cancer susceptibility loci on chromosomes 5p15 and 15q25 in an African-American population.
Lung cancer (Amsterdam, Netherlands) - 1 Aug 2016
Zanetti Krista A, Wang Zhaoming, Aldrich Melinda, Amos Christopher I, Blot William J, Bowman Elise D, Burdette Laurie, Cai Qiuyin, Caporaso Neil, Chung Charles C, Gillanders Elizabeth M, Haiman Christopher A, Hansen Helen M, Henderson Brian E, Kolonel Laurence N, Marchand Loic Le, Li Shengchao, McNeill Lorna Haughton, Ryan Bríd M, Schwartz Ann G, Sison Jennette D, Spitz Margaret R, Tucker Margaret, Wenzlaff Angela S, Wiencke John K, Wilkens Lynne, Wrensch Margaret R, Wu Xifeng, Zheng Wei, Zhou Weiyin, Christiani David, Palmer Julie R, Penning Trevor M, Rieber Alyssa G, Rosenberg Lynn, Ruiz-Narvaez Edward A, Su Li, Vachani Anil, Wei Yongyue, Whitehead Alexander S, Chanock Stephen J, Harris Curtis C
Abstract excerpt
OBJECTIVES: Genome-wide association studies (GWAS) of lung cancer have identified regions of common genetic variation with lung cancer risk in Europeans who smoke and never-smoking Asian women. This study aimed to conduct a GWAS in African Americans, who have higher rates of lung cancer despite smoking fewer cigarettes per day when compared with Caucasians. This population provides a different genetic...
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