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Article

Racial differences in the association between SNPs on 15q25.1, smoking behavior, and risk of non-small cell lung cancer.

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer - 1 Oct 2009

Schwartz Ann G, Cote Michele L, Wenzlaff Angela S, Land Susan, Amos Christopher I

Abstract excerpt

INTRODUCTION: Three genome-wide association studies identified a region on chromosome 15q25.1 associated with lung cancer and measures of nicotine addiction. This region includes nicotinic acetylcholine receptor subunit genes CHRNA3 and CHRNA5. These studies were conducted in European or European...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19641473
DOI: 10.1097/JTO.0b013e3181b244ef
PMCID: PMC3768000

Genes

CHRNA3
CHRNA5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Prepared record publication-19641473-2026-09-05.1. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 5 Sept 2026.

Related research

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Racial differences in the association between SNPs on 15q25.1, smoking behavior, and risk of non-small cell lung cancer.PMID 19641473Read ↗

Nicotinic acetylcholine receptor region on chromosome 15q25 and lung cancer risk among African Americans: a case-control study.Semantic proximity Read ↗

Association study of nicotinic acetylcholine receptor genes identifies a novel lung cancer susceptibility locus near CHRNA1 in African-Americans.Semantic proximity Read ↗

Targeted sequencing of chromosome 15q25 identified novel variants associated with risk of lung cancer and smoking behavior in Chinese.Semantic proximity Read ↗

Genome-wide association study confirms lung cancer susceptibility loci on chromosomes 5p15 and 15q25 in an African-American population.Semantic proximity Read ↗

Multiple independent loci at chromosome 15q25.1 affect smoking quantity: a meta-analysis and comparison with lung cancer and COPD.Semantic proximity Read ↗

Multiple cholinergic nicotinic receptor genes affect nicotine dependence risk in African and European Americans.Semantic proximity Read ↗

Fine mapping of chromosome 15q25.1 lung cancer susceptibility in African-Americans.Semantic proximity Read ↗

The CHRNA5-A3 region on chromosome 15q24-25.1 is a risk factor both for nicotine dependence and for lung cancer.Semantic proximity Read ↗

A case-control study of a sex-specific association between a 15q25 variant and lung cancer risk.Semantic proximity Read ↗

Chromosome 15q25 (CHRNA3-CHRNB4) Variation Indirectly Impacts Lung Cancer Risk in Chinese Males.Semantic proximity Read ↗

A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25.Semantic proximity Read ↗

Genome-wide meta-analyses of smoking behaviors in African Americans.Semantic proximity Read ↗

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